total antibodies s protein trimer (VECTOR-BEST)
Structured Review

Total Antibodies S Protein Trimer, supplied by VECTOR-BEST, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/total+antibodies+s+protein+trimer/total+antibodies+s+protein+trimer/med_rxiv__2022__02__08__22270658-44-26-29
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Safety and immunogenicity of inactivated whole virion vaccine CoviVac against COVID-19: a multicenter, randomized, double-blind, placebo-controlled phase I/II clinical trial"
Article Title: Safety and immunogenicity of inactivated whole virion vaccine CoviVac against COVID-19: a multicenter, randomized, double-blind, placebo-controlled phase I/II clinical trial
Journal: medRxiv
doi: 10.1101/2022.02.08.22270658
Figure Legend Snippet: Anti-SARS-CoV-2 antibody levels following immunization of 27 randomly selected participants who were seronegative at screening. nAB titers in NT (A); and positivity coefficients for ELISA and CMIA kits: anti-S trimer total antibodies ELISA (Vector-Best) (B); anti-RBD total antibodies ELISA (CoronaPass) (C); anti-RBD IgG CMIA (Beckman) (D); and anti-N IgG CMIA (Abbot) (E). Black line – Mean, whiskers – SD. Blue area signifies a positive threshold (grey zone) for each test. Black dots represent the results from sera samples from 6 randomly selected participants from Placebo Group obtained in the same tests in parallel (with Vector-Best sera from 3 participants were tested). Purple dots represent 4 samples of convalescent sera used as positive controls.
Techniques Used: Enzyme-linked Immunosorbent Assay, Plasmid Preparation
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Enzyme-linked Immunosorbent Assay:Article Title: Safety and immunogenicity of inactivated whole virion vaccine CoviVac against COVID-19: a multicenter, randomized, double-blind, placebo-controlled phase I/II clinical trial Article Snippet: IgG antibodies to receptor-binding domain (RBD) of the spike protein (S) were detected using Access SARS-CoV-2 IgG CMIA (Beckman, USA). .. Serum samples from randomly selected participants were additionally tested in ELISA for total antibodies against RBD with CoronaPass Total (Genetico, Russia) and for total antibodies to |